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Recent Publications

Y. Lu, J. Wu, S. Chen, S. Sun, Y.B. Ma, Q. Ouyang, D.J. Finley, M.W. Kirschner, Y. Mao. Conformational landscape of the p28-bound human proteasome regulatory particle. bioRxiv: 088492; doi: http://dx.doi.org/10.1101/088492 (2016). Download

S. Chen, J. Wu, Y. Lu, Y.B. Ma, B.H. Lee, Z. Yu, Q. Ouyang, D.J. Finley, M.W. Kirschner, Y. Mao. Structural basis for dynamic regulation of the human 26S proteasome. Proc. Natl. Acad. Sci. USA 113, 12991-12996 (2016). Download

Y. Xu, J. Wu, C.C. Yin, Y. Mao. Unsupervised cryo-EM data clustering through adaptively constrained K-means algorithm. PLoS ONE 11, e0167765 (2016). doi: 10.1371/journal.pone.0167765. arXiv: 1609.02213 [q-bio.QM]. Download

Y. Zhu, Q. Ouyang, Y. Mao. A deep learning approach to single-particle recognition in cryo-electron microscopy. arXiv: 1605.05543 [physics.data-an] (2016). Download

J. Wu, Y. Ma, C. Congdon, B. Brett, S. Chen, Q. Ouyang, Y. Mao. Unsupervised single-particle deep classification via statistical manifold learning. arXiv: 1604.04539 [physics.data-an] (2016). Download Supplementary Data

A. Lu, Y. Li, F.I. Schmidt, Q. Yin, S. Chen, T.M. Fu, A.B. Tong, Y. Mao, H. Wu. Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism. Nature Struct. Mol. Biol. 23, 416-425 (2016). Download

L. Zhang, S. Chen, J. Ruan, J. Wu, A.B. Tong, Q. Yin, Y. Li, L. David, A. Lu, W.L. Wang, C. Marks, Q. Ouyang, X. Zhang, Y. Mao*, H. Wu*. Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Science 350, 404-409 (2015). Download

Z. Yu, W.L. Wang, L. R. Castillo-Menendez, J. Sodroski, Y. Mao*. On the parameters affecting dual-target-function evaluation of single-particle selection from cryo-electron micrographs. arXiv:1509.06863 [q-bio.QM] (2015). Download